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How aneurysm shape affects occlusion success after flow diverter placement
Kornelia M Kliś1, Igor Szydłowski2, Jerzy Gąsowski3
1Department of Neurosurgery and Neurotraumatology, Jagiellonian University Medical College, Kraków, Poland. kornelia.klis@uj.edu.pl.
Neuroradiology
|November 5, 2025
Summary
Flow diverters (FD) are used for intracranial aneurysms, but complete occlusion is difficult. Aneurysm shape, specifically Gaussian curvature entropy and Zernike Moment Invariants energy, influences FD treatment success.
Area of Science:
- Neurosurgery
- Endovascular techniques
- Medical imaging analysis
Background:
- Flow diverters (FD) are a key endovascular treatment for intracranial aneurysms.
- Achieving complete aneurysm occlusion with FDs remains a clinical challenge.
Purpose of the Study:
- To quantitatively analyze three-dimensional aneurysm morphology.
- To assess the influence of aneurysm morphology on complete occlusion rates after FD placement.
Main Methods:
- Retrospective single-center study of patients treated with FDs (2019-2022).
- Comparison of quantitative 3D morphological parameters between incompletely and completely occluded aneurysms.
- Calculated parameters included curvature, Writhe number, and Zernike Moment Invariants energy.
Main Results:
- Incompletely occluded aneurysms exhibited higher Aspect Ratio, Size Ratio, Gaussian curvature entropy, and Zernike Moment Invariants energy.
- Gaussian curvature entropy (OR=2.06) and Zernike Moment Invariants energy (OR=3.02) were independently associated with incomplete occlusion.
Conclusions:
- Quantitative aneurysm dome morphology descriptors, specifically Gaussian curvature entropy and Zernike Moment Invariants energy, are linked to occlusion outcomes.
- These morphological factors may predict the likelihood of complete aneurysm occlusion post-FD treatment.
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