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Updated: Jan 12, 2026

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Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
Published on: January 16, 2019
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A mixed methods study protocol evaluating early screening, triaging, risk assessment and health optimisation in
Katie Gilchrist1, Bo Hou1, James Bedford2
1Research Department of Targeted Intervention, Division of Surgery and Interventional Science, Central London Patient Safety Research Collaboration (PSRC), University College London, London, United Kingdom.
Plos One
|November 5, 2025
Summary
NHS England
Area of Science:
- Surgical pathway optimization
- Healthcare system improvement
- Patient safety research
Background:
- Millions of UK surgeries annually carry risks, with late preoperative assessments limiting patient optimization.
- Early preoperative screening aims to mitigate risks and improve outcomes.
- A new NHS England program mandates early screening, risk assessment, and health optimization.
Purpose of the Study:
- To evaluate the implementation and impact of the new NHS England early preoperative screening program.
- To identify barriers and facilitators to program implementation.
- To assess the program's effect on patient-centered outcomes.
Main Methods:
- Mixed methods research design combining qualitative and quantitative approaches.
- Formative implementation evaluation using staff and patient interviews and meeting observations.
- Interrupted time series analysis of routinely collected electronic health records for patient outcomes.
Main Results:
- Qualitative data will reveal implementation barriers, facilitators, and user experiences.
- Quantitative analysis will assess the program's impact on key patient outcomes.
- Outcomes include days alive out of hospital, length of stay, and readmission rates.
Conclusions:
- The study will offer valuable insights into implementing early preoperative screening programs.
- Findings will inform future strategies for enhancing surgical patient safety and efficiency.
- Understanding staff and patient experiences is crucial for successful program adoption.
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