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Sarocladium implicatum: an unusual agent of opportunistic infection in a COVID-19 patient
Gilberto Gambero Gaspar1, Ludmilla Tonani2, Patrícia Helena Grizante Barião2
1Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Medicina Social, Ribeirão Preto, São Paulo, Brazil.
Abstract:
Sarocladium spp. are filamentous fungi commonly associated with plant diseases and only rarely cause hyalohyphomycosis in humans. Immunosuppressed patients are at risk for this infection, which typically presents with skin and subcutaneous lesions that may eventually disseminate to internal organs. This study reports a case of a man in intensive care following SARS-CoV-2 infection. During hospitalization, he developed neutropenia, persistent fever, and a cavitary lung lesion. Sarocladium spp. was isolated from blood cultures, and the patient was treated with voriconazole, leading to a successful cure. To our knowledge, this is the first reported case of Sarocladium implicatum infection in a COVID-19 patient, underscoring the importance of monitoring opportunistic fungal infections in immunocompromised individuals, particularly during epidemics and pandemics.
Insights
This study details a rare human fungal infection caused by Sarocladium spp. in an intensive care patient with SARS-CoV-2, highlighting the need for vigilance against opportunistic infections in immunocompromised individuals.
Area of Science:
- Mycology
- Infectious Diseases
- Critical Care Medicine
Background:
- Sarocladium spp. are filamentous fungi primarily known for causing plant diseases.
- Human infections (hyalohyphomycosis) are rare, typically affecting immunosuppressed individuals.
- These infections can manifest as cutaneous lesions and potentially disseminate to internal organs.
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