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Related Experiment Video

Updated: Jan 12, 2026

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A Tracked High-Resolution Ultrasound Endoscope for Minimally Invasive Brain Surgery.

Annika Benson1, Robert Weaver1, Adrienne Weeks2

  • 1School of Biomedical Engineering, Dalhousie University, Halifax, Nova Scotia, Canada.

Operative Neurosurgery (Hagerstown, Md.)
|November 5, 2025
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A new miniature ultrasound endoscope enhances neurosurgery by providing real-time brain visualization. This novel imaging adjunct successfully differentiated tumor from healthy tissue and integrated with navigation systems.

Keywords:
AneurysmGlioblastomaHigh resolutionMinimally invasive surgerySurgical navigationTumorUltrasound

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Area of Science:

  • Neurosurgery
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Limitations exist in current neurosurgical guidance technology.
  • A novel miniature, high-resolution, tracked ultrasound (US) imaging endoscope was developed.
  • This device aims to improve intraoperative visualization within narrow surgical pathways.

Purpose of the Study:

  • To describe the fabrication and preliminary testing of a novel intraoperative imaging adjunct.
  • To evaluate the device's potential to enhance neurosurgery by providing precise, real-time brain visualization.
  • To integrate the US endoscope with a surgical navigation system (SNS).

Main Methods:

  • Developed a miniature (3.8 × 4 mm) 30 MHz phased array ultrasound probe with 64 elements.
  • Tested probe performance, safety, and intraoperative visualization capabilities in 3 adult neurosurgery cases.
  • Integrated the US probe with a commercial SNS and validated tracking in a brain phantom.

Main Results:

  • The probe achieved axial and lateral resolutions of 38 and 113 µm, respectively.
  • Successfully differentiated tumor from healthy tissue and identified residual tumor during resection.
  • Demonstrated good agreement (within 2.90 mm) between navigated MRI and US images in a brain phantom.

Conclusions:

  • The developed imaging system shows potential as a novel adjunct for neurosurgical guidance.
  • This first-of-its-kind system offers precise, real-time visualization.
  • Further clinical testing is required to fully validate the efficacy of this neurosurgical tool.