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Related Concept Videos

Rh Blood Group01:19

Rh Blood Group

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The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
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Related Experiment Video

Updated: Jan 12, 2026

Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface
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The Complexity of Weak Rhesus Positivity in Pregnancy: Challenges and Management-A Case Report.

Meghan Warner1, Nicole Villa1, Jordan Winebrenner1

  • 1Edward Via College of Osteopathic Medicine - Carolinas Campus, Spartanburg, South Carolina.

Clinical Practice and Cases in Emergency Medicine
|November 5, 2025
PubMed
Summary

Identifying weak Rh positivity in pregnant patients is crucial for appropriate Rh immunoglobulin (RhIG) administration. This helps prevent hemolytic disease of the newborn and optimizes RhIG resource allocation for Rh-negative women.

Area of Science:

  • Obstetrics and Gynecology
  • Immunology
  • Transfusion Medicine

Background:

  • Rhesus (Rh) antigen status determination is vital in prenatal care for Rh immunoglobulin (RhIG) administration.

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  • RhIG prevents Rh alloimmunization, a cause of hemolytic disease of the newborn (HDN).
  • Weakly Rh+ phenotypes complicate accurate Rh status categorization.