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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Infant emotionality and maternal depression at 6 months postpartum
Karley Mariano1, Sandra J Weiss1
1Department of Community Health Systems, School of Nursing, University of California, San Francisco, San Francisco, CA, USA.
Background:
Postpartum depression is a global concern associated with multiple complications, including the risk of suicide. Beyond the suffering experienced by women with postpartum depression, research provides evidence of its negative impact on mother-infant relationships. However, little attention has been given to the potential impact of infant characteristics on development or severity of postpartum depression.
Objective:
The purpose of this study was to determine if greater infant emotionality is associated with symptoms of maternal depression at 6 months postpartum. Emotionality was defined as infant negative affectivity and emotional reactivity in response to a stressor.
Methods:
At 6 months postpartum, women completed questionnaires to assess their history of depression, current depressive symptoms, and infant's negative affectivity. Mother and infant also participated in a video-recorded, stressor protocol (the Still Face Paradigm) that was later coded for infant emotional reactivity, using a standardized measure.
Results:
Postpartum depression ranged from asymptomatic to severe, with 10 % of women meeting criteria for Major Depressive Disorder. Linear regression indicated that infant negative affectivity (β = 0.93, p = 0.002), but not emotional reactivity, was associated with mother's depressive symptoms at 6 months postpartum. Neither a woman's previous diagnosis of depression nor her prenatal depression predicted infant negativity, supporting the directional effect of infant negativity on postpartum depression.
Conclusions:
Findings indicate the need for early assessment of infant temperament and mother-infant interactions, especially among women with a history of depression. Early intervention to assist mothers in caring for infants with more challenging affective behaviors may prevent development or worsening of postpartum depression.
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