Chorionic Bump as a Marker for Early Pregnancy Loss: A Retrospective Cohort Study

Area of Science:

• Obstetrics and Gynecology
• Reproductive Medicine
• Medical Imaging

Background:

• A chorionic bump (CB) is an uncommon finding during early first-trimester obstetric ultrasounds.
• Understanding the prevalence and clinical significance of CB is important for early pregnancy management.

Purpose of the Study:

• To estimate the prevalence of chorionic bumps (CB) in early pregnancy.
• To investigate the association between the presence of a chorionic bump and the risk of early pregnancy loss.

Main Methods:

• Retrospective analysis of 2589 pregnancies over a 3-year period.
• Calculation of chorionic bump prevalence.
• Statistical analysis to assess the association between CB and early pregnancy loss, controlling for potential confounders.

Main Results:

• The overall prevalence of chorionic bumps was 1.1% (28/2589 pregnancies).
• No significant differences were observed in baseline demographics, obstetric measurements, or mode of conception between patients with and without CB.
• The presence of a chorionic bump was not statistically associated with an increased odds of early pregnancy loss (adjusted OR 1.3; 95% CI 0.4-3.6).

Conclusions:

• Chorionic bumps are an uncommon finding in early first-trimester ultrasounds with a prevalence of 1.1%.
• The study did not find a statistically significant association between chorionic bumps and early pregnancy loss.
• These findings suggest that a chorionic bump may not be an indicator of adverse pregnancy outcome.