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Wound Healing and Management Considerations in the Pediatric Surgical Patient

Norah E Liang1, Serena L Jing2, Elijah J Suh1

  • 1Department of Surgery, Division of Pediatric Surgery, Stanford University School of Medicine, Stanford, California, USA.

Advances in Wound Care
|November 5, 2025
PubMed

Insights

Pediatric wound healing differs significantly from adult healing due to unique physiology and development. Understanding these differences is crucial for optimizing care in infants, children, and adolescents.

Area of Science:

  • Pediatric surgery
  • Wound healing biology
  • Developmental physiology

Background:

  • Pediatric wound healing is influenced by unique physiological, growth, and developmental factors.
  • Existing literature on wound healing primarily focuses on adults, with limited data specific to pediatric populations.
  • Age-specific considerations are critical from neonates to adolescents.

Purpose of the Study:

  • To review primary literature on aging and wound healing in pediatric patients.
  • To highlight clinical wound healing applications across pediatric age ranges.
  • To characterize differences in wound healing biology between pediatric age groups and adults.

Main Methods:

  • Literature review of primary research on aging and wound healing.
  • Characterization of age-specific wound healing biology.
  • Discussion of evidence-based guidelines for pediatric wound management.

Main Results:

  • Significant differences exist in wound healing biology between infants, adolescents, and adults.
  • Pediatric surgical patients have specialized wound care needs requiring tailored strategies.
  • Multidisciplinary approaches and understanding unique considerations are key for optimal outcomes.

Conclusions:

  • Optimizing pediatric wound care necessitates understanding age-specific biology and unique physiological, psychological, and social factors.
  • Future research should focus on pediatric-specific clinical trials for emerging technologies and regenerative medicine.
  • Addressing knowledge gaps in topical agent pharmacokinetics is essential for advancing pediatric wound care.
Abstract

Keywords:
fibrosispediatricstoma carewound carewound healing

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