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Published on: November 1, 2007
Incidence and Associated Factors for Post-Transplant Diabetes Mellitus (PTDM) After Kidney Transplant in PMK-KT
Pitchamon Inkong1, Nitichai Duenchai1, Naowanit Nata1
1Department of Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand.
Background:
Post-transplant diabetes mellitus (PTDM) presents a growing global health challenge. Limited understanding of PTDM in Asians needs to be explored.
Objectives:
This study aims to identify the cumulative incidence of PTDM and the associated risk factors in kidney transplant recipients.
Methods:
This retrospective cohort was performed at the Kidney Transplant Center of Phramongkutklao Hospital (PMK-KT), Thailand, from January 1989 to January 2022. Demographic information, comorbid disorders, laboratory test results, pharmacological treatments, and drug concentrations were recorded. Utilizing multiple logistic regression analysis, we assessed the risk of PTDM.
Results:
The total of 174 KT recipients was eligible for analysis. The cumulative incidence of PTDM was 16.7% (95% CI: 11.46%-23.05%). Multivariable logistic regression identified chronic hepatitis C, Everolimus usage, graft rejection, and post-transplant hypomagnesemia as predictors of PTDM. The overall mortality was 20.5% (95% CI: 14.62%-27.43%).
Conclusion:
A slightly increased cumulative incidence of PTDM was observed. Several risk factors were identified.
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