Rosai-Dorfman disease presenting without systemic symptoms in childhood

Rosai-Dorfman disease (RDD) is a rare, non-Langerhans cell histiocytosis that typically presents with massive lymphadenopathy. We report a case in a child who presented in his early childhood with painless cervical lymphadenopathy. On further imaging, he was found to have abdominal and hilar lymphadenopathy. Despite the extent of nodal disease, the child remained asymptomatic. Fine-needle aspiration cytology confirmed the diagnosis of RDD, and was treated with conservative management. The child has remained asymptomatic over 1 year of follow-up, highlighting the benign nature and self-limiting nature of the disease in some paediatric cases.