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ACR Appropriateness Criteria® Hematospermia.
, Carla Harmath1, Brian C Allen2
1The University of Chicago, Chicago, Illinois.
Journal of the American College of Radiology : JACR
|November 5, 2025
Summary
Hematospermia evaluation depends on patient age and symptoms. Imaging is recommended for symptomatic or persistent cases in older patients to identify causes.
Area of Science:
- Radiology
- Urology
- Medical Imaging
Background:
- Hematospermia is an uncommon reason for imaging referral.
- Evaluation requires considering patient age, symptom duration, and associated signs.
- Younger patients with transient, asymptomatic hematospermia typically need clinical reassurance.
Purpose of the Study:
- To provide guidance on appropriate imaging modalities for hematospermia evaluation.
- To outline criteria for selecting imaging based on clinical presentation.
- To address variations in initial imaging approaches.
Main Methods:
- Literature review and clinical consensus inform imaging recommendations.
- Utilizes the American College of Radiology Appropriateness Criteria.
- Employs methodologies like Grading of Recommendations Assessment, Development, and Evaluation (GRADE) and the RAND/UCLA Appropriateness Method.
Main Results:
- Imaging is indicated for symptomatic, persistent, or older patients with hematospermia.
- Guidelines help determine the most suitable imaging modalities for identifying potential etiologies.
- Expert opinion serves as a primary source when literature is limited.
Conclusions:
- Clinical factors guide the decision for imaging in hematospermia.
- Evidence-based guidelines and expert consensus are crucial for appropriate imaging selection.
- Tailored imaging strategies improve the evaluation of hematospermia.

