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A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)
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Approaches and Strategies for Pediatric Injury Prevention.

Lois K Lee1, Flaura K Winston2

  • 1Department of Pediatrics and Emergency Medicine, Harvard Medical School; Division of Emergency Medicine, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.

Pediatric Clinics of North America
|November 5, 2025
PubMed
Summary
This summary is machine-generated.

Preventable injuries significantly impact children and youth. A systematic approach using the Haddon Matrix and Injury Equity Framework, along with the "7 Es" of prevention, can guide effective strategies.

Keywords:
Injury preventionTraumaUnintentional injuries

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Area of Science:

  • Public Health
  • Pediatric Medicine
  • Injury Prevention Research

Background:

  • Injuries represent a primary cause of morbidity and mortality in pediatric populations.
  • A significant proportion of these injuries are preventable through targeted interventions.
  • Existing prevention frameworks lack a comprehensive, systematic approach.

Purpose of the Study:

  • To outline a systematic, scientific approach for designing, implementing, and evaluating pediatric injury prevention strategies.
  • To introduce the Haddon Matrix and Injury Equity Framework as foundational tools for injury prevention.
  • To present the "7 Es" of injury prevention as a comprehensive model for intervention development.

Main Methods:

  • Systematic review and synthesis of injury prevention literature.
  • Application of the Haddon Matrix to analyze injury causation and prevention opportunities.
  • Integration of the Injury Equity Framework to address social determinants of health in injury prevention.
  • Development of the "7 Es" framework (Economics, Education, Empowerment, Enforcement, Engineering, Environment, Equity) for comprehensive intervention design.

Main Results:

  • The Haddon Matrix and Injury Equity Framework provide a robust structure for injury prevention.
  • The "7 Es" framework offers a multi-faceted approach to developing effective injury prevention strategies.
  • Pediatric clinicians are identified as crucial stakeholders in advancing injury prevention research and advocacy.

Conclusions:

  • A systematic, evidence-based approach is essential for effective pediatric injury prevention.
  • The integrated Haddon Matrix, Injury Equity Framework, and "7 Es" model provide a comprehensive foundation for interventions.
  • Empowering pediatric clinicians is vital for advancing injury prevention at multiple levels.