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[Translated article] Sepsis and septic shock.

Carla Bastida1, Amaia Egües Lugea2, Aurora Fernández Polo3

  • 1Servicio de Farmacia, Área del Medicamento, Hospital Clínic de Barcelona, Barcelona, Spain.

Farmacia Hospitalaria : Organo Oficial De Expresion Cientifica De La Sociedad Espanola De Farmacia Hospitalaria
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Sepsis and septic shock are life-threatening conditions. Early recognition and prompt treatment, including infection control and perfusion restoration, are vital for patient survival and recovery.

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Antimicrobial agentsFluid therapyFluidoterapiaGlucocorticoidesGlucocorticoidsSepsisSeptic shockShock sépticoTratamiento antimicrobianoVasopresoresVasopressor agents

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Area of Science:

  • Critical care medicine
  • Infectious diseases
  • Pharmacology

Background:

  • Sepsis and septic shock represent significant global health challenges.
  • High morbidity and mortality rates are associated with these conditions.
  • Timely interventions within the initial hours are critical for improving patient outcomes.

Purpose of the Study:

  • To emphasize the importance of early identification and management of sepsis.
  • To outline the core components of sepsis treatment.
  • To highlight the essential role of clinical pharmacists in optimizing pharmacotherapy for sepsis patients.

Main Methods:

  • Review of current sepsis management strategies.
  • Focus on infection control, hemodynamic support, and adjunctive therapies.
  • Emphasis on the pharmacist's role in therapeutic validation.

Main Results:

  • Early identification and management significantly improve clinical outcomes.
  • Multifaceted treatment approach is necessary for sepsis.
  • Pharmacists play a key role in ensuring effective and safe medication use.

Conclusions:

  • Prompt diagnosis and intervention are paramount in sepsis care.
  • Comprehensive treatment strategies are essential.
  • Clinical pharmacists are integral to the multidisciplinary team for optimizing sepsis management and patient recovery.