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Updated: Jan 12, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Phototherapy exposure variability in extremely preterm neonates due to different treatment protocols and devices:
Daniele De Luca1,2, Costanza Neri3, Vanessa Monin3
1Physiopathology and Therapeutic Innovation INSERM-U999, Paris Saclay University, Paris, France. dm.deluca@icloud.com.
Objective:
To investigate the phototherapy exposure in extremely preterm infants using different treatment protocols and devices.
Design:
Cross-sectional observational study enrolling extremely preterm infants requiring light emitting diodes (LED) phototherapy during the first week of life. The duration of phototherapy applying various expert opinion-based treatment guidelines was calculated. Irradiance was measured, and spectral power was estimated.
Results:
Forty-two preterm infants were studied. The phototherapy duration changed depending on the treatment protocol (overall p < 0.001) and ranged from 0 to 72 h, with a median coefficient of variation of 66.6 [44-124]%. The spectral power was significantly different depending on the LED device (overall p < 0.001) and ranged from 8.6 to 17.8 mW/nm, with a median coefficient of variation of 18.1 [18-18.3]% CONCLUSIONS: The phototherapy exposure of preterm infants significantly varies both as cumulative duration of therapy and spectral power, due to different treatment protocols and devices.
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