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Related Concept Videos

Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

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The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
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  7. Paediatrics
  9. Infant And Child Health
  11. Chinese And Global Trends In Pediatric Spinal Cord Injury Burden (1990-2021) With Projections To 2045

Chinese and global trends in pediatric spinal cord injury burden (1990-2021) with projections to 2045

You-Ping Tao1, Chen-Hao Zhao2, Ji-Gong Wu2

  • 1Department of Spine Surgery, The Ninth Medical Center of Chinese PLA General Hospital, No. 9 Anxiangbeili, ChaoYang District, Beijing, 100101, China. taoyoupingmail@126.com.

World Journal of Pediatrics : WJP
|November 5, 2025

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Enhancing the Development and Growth of Infant Cerebral Palsy Rats Using Selective Spinal Manipulations
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View abstract on PubMed

Summary
This summary is machine-generated.

Global pediatric spinal cord injury burden decreased from 1990 to 2021, with declines in incidence, prevalence, and disability. However, China is projected to see an increase by 2045, highlighting the need for targeted interventions.

Area of Science:

  • Epidemiology
  • Public Health
  • Traumatology

Background:

  • Spinal cord injury (SCI) is a significant global health concern with diverse causes and risk factors.
  • Limited comprehensive analyses exist on pediatric SCI trends in China and worldwide.

Purpose of the Study:

  • To analyze temporal trends in pediatric SCI burden (incidence, prevalence, years lived with disability) globally and in China from 1990 to 2021.
  • To project future pediatric SCI burden to 2045.
  • To identify key demographic and regional factors influencing SCI trends.

Main Methods:

  • Utilized Global Burden of Disease (GBD) 2021 data for analyses from 1990 to 2021.
  • Employed joinpoint regression to identify significant trend changes.
  • Applied a Bayesian age-period-cohort model for future burden projections to 2045.
Keywords:
BurdenGlobal disease burdenPediatricsProjection analysis

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Main Results:

  • Global pediatric SCI incidence, prevalence, and YLD rates significantly decreased between 1990 and 2021 (AAPC ranging from -1.13% to -1.37%).
  • The highest burden was observed in males, adolescents (15-19 years), and high-sociodemographic index regions, with falls as the leading cause.
  • China mirrored global declining trends during this period, but is projected to experience an upward trend by 2045.

Conclusions:

  • Despite overall global declines, persistent disparities in pediatric SCI burden and causes necessitate targeted prevention and rehabilitation strategies.
  • Equitable resource allocation is crucial, especially for high-risk groups and regions anticipating increasing SCI burdens.
Spinal cord injury