Related Experiment Video
Updated: May 6, 2026

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex
Published on: July 4, 2018
Differences in symptoms and problems experienced by patients with a life-threatening disease in specialized
Maiken Bang Hansen1,2,3, Mogens Groenvold4,5, Mette Raunkiær6
1Palliative Care Research Unit, Department of Geriatrics and Palliative Medicine GP, Copenhagen University Hospital - Bispebjerg and Frederiksberg, University of Copenhagen, Copenhagen, Denmark. maiken.bang.hansen@regionh.dk.
Background:
Patients with a life-threatening disease often experience palliative care needs (symptoms and problems) before death, and those with the most complex needs should be those who get access to specialized palliative care. To examine if that is the case, studies are needed comparing palliative care needs of patients with life-threatening cancer and non-cancer diseases admitted to specialized palliative care to patients receiving basic palliative care.
Aims:
To compare palliative care needs among patients with a life-threatening disease admitted to specialized palliative care and patients receiving basic palliative care.
Design:
A secondary data analysis of symptoms/problems reported by patients in basic palliative care or at admittance to specialized palliative care in Denmark. Ordinal logistic regression was performed to study differences in the probability of experiencing each symptom/problem among patients receiving specialized palliative care vs. basic palliative care, controlled for possible confounders.
Setting/Participants:
Patients with a life-threatening disease who completed the EORTC QLQ-C15-PAL questionnaire.
Results:
The study included 6367 patients. The odds of experiencing symptoms, impaired physical functioning, impaired emotional functioning, and poor quality of life were higher at admittance to specialized palliative care compared to an ongoing basic palliative care, especially impaired physical functioning (OR 8.3, 95% CI 6.6-10.5) and fatigue (OR 5.1, 95% CI 4.1-6.5).
Conclusions:
Patients in specialized palliative care had higher levels of symptoms and problems than patients with a life-threatening disease receiving basic palliative care, especially non-cancer patients. Future research should study changes in symptoms/problems during the disease trajectory among patients with life-threatening diseases to improve referrals to specialized palliative care.
Related Concept Videos
Tertiary Healthcare System
Continuing Care
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
Ethical Issues
Ethical Concerns in Healthcare:
Ethical Dilemmas II
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:

