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From Incision to Healing: An Evidence-Based Review of Scar Optimization in Upper Blepharoplasty
Ali Aghajani1, Leila Babaei2, Bahram Eshraghi3
1Department of Ophthalmology, Isfahan eye research center, Isfahan University of medical sciences, Isfahan, Iran. aliaghajani_y@yahoo.com.
Aesthetic Plastic Surgery
|November 5, 2025
Summary
Optimizing upper blepharoplasty outcomes involves meticulous surgical technique and individualized suture selection. Evidence-based postoperative care is key, while many routine interventions lack scientific backing for improved scar quality.
Area of Science:
- Plastic Surgery
- Ophthalmology
- Evidence-Based Medicine
Background:
- Upper blepharoplasty is a common aesthetic procedure where scar quality significantly impacts patient satisfaction.
- Minimizing complications like wound dehiscence, milia, and scarring is crucial for optimal cosmetic results.
Purpose of the Study:
- To review and evaluate surgical and postoperative strategies for enhancing cosmetic outcomes in upper blepharoplasty.
- To assess the evidence supporting various techniques and interventions for scar quality improvement.
Main Methods:
- Systematic review of studies comparing incision modalities (scalpel, RF, CO2 laser) and suture techniques (interrupted, subcuticular, running).
- Evaluation of suture materials (absorbable vs. non-absorbable) and topical agents (silicone creams).
- Assessment of evidence for postoperative modalities (botulinum toxin, triamcinolone, cold compresses, dressings).
Main Results:
- No significant difference in final scar appearance between different incision modalities.
- Interrupted and subcuticular sutures show better short-term scar scores than running techniques; tension relief is important.
- Silicone creams aid hypertrophic scar reduction; botulinum toxin and triamcinolone lack sufficient evidence. Many postoperative modalities offer minimal benefit.
Conclusions:
- Optimal upper blepharoplasty results depend on meticulous surgical technique, individualized suture choice, tension management, and evidence-based care.
- Reconsideration of routine interventions lacking scientific backing is advised in favor of proven efficacy for improved scar outcomes.
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