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Updated: Jan 12, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Timing of Antenatal Corticosteroid Administration and Neonatal Outcomes
Nir Melamed1, Kellie E Murphy, Christy Pylypjuk
1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynaecology, Sunnybrook Health Sciences Centre (N.M.), and Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynaecology, Mount Sinai Hospital (K.E.M.), Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario; Department Obstetrics, Gynecology and Reproductive Sciences, University of Manitoba, Winnipeg (C.P.); Department of Pediatrics, Surrey Memorial Hospital, University of British Columbia, Vancouver (R.S.); Department of Neonatology, CHU Sainte-Justine, Montreal, Quebec (G.E.); and Maternal-Infant Care Research Centre (MiCare), Mount Sinai Hospital (E.W.Y., P.S.S.); and Department of Neonatology, Mount Sinai Hospital, Temerty Faculty of Medicine, University of Toronto (P.S.S.), Toronto, Ontario, Canada.
Abstract:
(Abstracted from JAMA Network Open 2025;8(5):e2511315) A single course of antenatal corticosteroids (ANCSs) is the most effective intervention for pregnant individuals at risk of preterm birth at <34 weeks of gestation. Although it is largely accepted that ANCS is most effective within 1 to 7 days before birth, it is unclear how soon within the first 24 hours the benefit takes effect, when the maximum effect is achieved, and how long the benefit will last after the first 7 days.
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