Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

5.0K
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
5.0K
Phases of Wound Repair01:28

Phases of Wound Repair

7.8K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
7.8K
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

2.1K
After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
2.1K
Whole Body Regeneration01:33

Whole Body Regeneration

4.0K
Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
4.0K
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

1.5K
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
1.5K
Fractures: Bone Repair01:27

Fractures: Bone Repair

4.9K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Indigenous Community Research Partnerships: The Development of an Open-access Training Resource to Promote Community-centered and -driven Research.

Progress in community health partnerships : research, education, and action·2026
Same author

Remodelling of the gut virome after long-term fasting.

NPJ biofilms and microbiomes·2026
Same author

Protocol for a SPIRIT extension for reporting Pragmatic and Explanatory trial protocols designed using the PRECIS tool. (SPIRIT-PRECIS).

Journal of clinical epidemiology·2026
Same author

Protocol for a CONSORT extension for reporting Pragmatic and Explanatory trials designed using the PRECIS tool. (CONSORT-PRECIS).

Journal of clinical epidemiology·2026
Same author

Genome sequencing identifies monogenic causes in adults with metabolic diseases.

Journal of the Endocrine Society·2026
Same author

Asymmetric synthesis of alkyl fluorides <i>via</i> biocatalytic reduction of α-fluoroenones and α-fluoroenoates.

Green chemistry : an international journal and green chemistry resource : GC·2026
Same journal

Hydrogel-Encapsulated Primed MSCs Enhance Regeneration in Full-Thickness Porcine Burn Wounds.

Tissue engineering. Part A·2026
Same journal

Unidirectional Porous Carbonate Apatite Fabricated by Gelatin-Based Freeze Casting for Bone Regeneration.

Tissue engineering. Part A·2026
Same journal

Regenerative Nanoscaffolds for Chronic Tympanic Membrane Perforation: From Bench to Clinical Translation.

Tissue engineering. Part A·2026
Same journal

Impact of IFN-γ-Pretreated Umbilical Cord Mesenchymal Stem Cells Implanted in Mesh on Pelvic Organ Prolapse.

Tissue engineering. Part A·2026
Same journal

The Driving Force of Hierarchical Collagen Fiber Formation: A Review of Tendon, Ligament, and Meniscus Mechanobiology.

Tissue engineering. Part A·2026
Same journal

A Nondestructive Raman Spectral Method for Temporal Tracking of Articular Cartilage Maturation.

Tissue engineering. Part A·2026
See all related articles

Related Experiment Video

Updated: Jan 12, 2026

Investigating Scarless Tissue Regeneration in Embryonic Wounded Chick Corneas
09:31

Investigating Scarless Tissue Regeneration in Embryonic Wounded Chick Corneas

Published on: May 2, 2022

2.3K

Regenerative Healing.

Michael V Sefton1, Malcolm King2, Alexandra King2

  • 1Institute of Biomedical Engineering and Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada.

Tissue Engineering. Part A
|November 6, 2025
PubMed
Summary
This summary is machine-generated.

Indigenous health and wellness is a holistic concept encompassing physical, mental, emotional, and spiritual well-being. Regenerative Healing offers a welcoming framework for discussing Indigenous health and research engagement.

Keywords:
indigenous healthregenerative healingwellness

More Related Videos

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

1.4K
Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis
06:36

Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis

Published on: August 21, 2020

13.9K

Related Experiment Videos

Last Updated: Jan 12, 2026

Investigating Scarless Tissue Regeneration in Embryonic Wounded Chick Corneas
09:31

Investigating Scarless Tissue Regeneration in Embryonic Wounded Chick Corneas

Published on: May 2, 2022

2.3K
Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

1.4K
Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis
06:36

Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis

Published on: August 21, 2020

13.9K

Area of Science:

  • Indigenous Health
  • Holistic Well-being
  • Community and Cultural Practices

Background:

  • Indigenous health and wellness integrates physical, mental, emotional, and spiritual dimensions.
  • It emphasizes interconnectedness, community, and cultural practices.

Purpose of the Study:

  • Introduce "Regenerative Healing" as a distinct, wholistic concept.
  • Propose Regenerative Healing as a more accessible framework for public engagement in health research.
  • Build trust between researchers and Indigenous communities.

Main Methods:

  • Conversations with First Nations and Métis Knowledge Holders across Canada.
  • Exploration of the concept of "Regenerative Healing".

Main Results:

  • "Regenerative Healing" emerged as a wholistic term from Indigenous Knowledge Holders.
  • This framework is distinct from "Regenerative Medicine".

Conclusions:

  • "Regenerative Healing" provides a welcoming and humble approach to discussing Indigenous health.
  • This framework can foster greater public trust and engagement in health and medical research.