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Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Related Experiment Video

Updated: Jan 12, 2026

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue
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Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue

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Radiotherapy for Keloids: A Comprehensive Narrative Review.

Hsin-Hua Nien1, Pei-Chieh Yu1, Yu-Hsiu Yen2

  • 1Department of Radiation Oncology, Cathay General Hospital, Taipei, TWN.

Cureus
|November 6, 2025
PubMed
Summary
This summary is machine-generated.

Surgical excision combined with radiotherapy effectively reduces keloid recurrence. This review details various radiotherapy methods for keloid management, aiding treatment strategy development.

Keywords:
brachytherapyelectronexternal beam radiotherapykeloidphotonradiotherapy

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Area of Science:

  • Dermatology
  • Radiation Oncology

Background:

  • Keloids cause significant discomfort and impact daily life.
  • Monotherapy for keloids often yields unsatisfactory results.
  • Surgical excision with adjuvant radiotherapy is a promising approach to reduce keloid recurrence.

Purpose of the Study:

  • To provide a narrative overview of radiation modalities for keloid management.
  • To summarize clinical evidence supporting the efficacy of different radiotherapy techniques.
  • To analyze factors influencing treatment outcomes and adverse effects.

Main Methods:

  • Literature review of studies on radiotherapy for keloid treatment.
  • Summarization of radiation treatment regimens, recurrence rates, and adverse effects by modality.
  • Analysis of factors affecting treatment efficacy.

Main Results:

  • Various radiation modalities and sources exist, each with unique properties and setup requirements.
  • Clinical outcomes and adverse effects vary across studies and treatment parameters.
  • Adjuvant radiotherapy following surgical excision demonstrates reduced keloid recurrence rates.

Conclusions:

  • A comprehensive understanding of radiation modality characteristics is crucial for developing tailored treatment strategies.
  • Institution-specific approaches, supported by multidisciplinary collaboration, can optimize keloid management.
  • Careful planning and delivery of radiotherapy alongside surgery can lead to favorable patient outcomes.