Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

451
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
451
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

774
Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
774
Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

544
Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
544
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

1.0K
Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
1.0K
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

268
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
268

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Establishing standards for controlled donation after circulatory determination of death in adults: the Bucharest international European Society for Organ Transplantation consensus.

Transplant international : official journal of the European Society for Organ Transplantation·2026
Same author

Assessment of therapeutic management practices in generalized and focal motor status epilepticus: An international survey in French, Belgian, and Swiss intensive care units.

Journal of intensive medicine·2026
Same author

Lipidomics analysis to assess metabolic complications in familial partial lipodystrophy type 2.

Diabetes research and clinical practice·2026
Same author

Between presence and influence: National survey stresses need to strengthen the involvement of paramedical professionals in ethical meetings.

Intensive & critical care nursing·2026
Same author

Prognostic Value of MRI Anatomical Radiologic Scores for One-Year Neurological Outcome After Severe Traumatic Brain Injury.

Neurocritical care·2026
Same author

Prolonged Grief Disorder Among Relatives of Deceased Patients in Intensive Care Unit During the French COVID-19 Lockdown: Results From the OLAF Study.

Omega·2026

Related Experiment Video

Updated: Jan 12, 2026

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

2.2K

cDCDD and Heart Procurement: Challenges from a French Critical Care Perspective.

Matthieu Le Dorze1,2, Julien Charpentier3, Gaëlle Cheisson4

  • 1Université Paris Cité, INSERM U942 MASCOT, Paris, France.

Transplant International : Official Journal of the European Society for Organ Transplantation
|November 6, 2025
PubMed
Summary

Controlled donation after circulatory death (cDCDD) offers a promising avenue for increasing organ availability. This paper addresses critical care challenges and ethical considerations for heart procurement in cDCDD, ensuring trust and compliance with the dead donor rule.

Keywords:
controlled donation after circulatory deathdead donor ruleend-of-life careheart procurementnormothermic regional perfusion

More Related Videos

Pre-clinical Model of Cardiac Donation after Circulatory Death
06:26

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

8.3K
Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
04:55

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

1.3K

Related Experiment Videos

Last Updated: Jan 12, 2026

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

2.2K
Pre-clinical Model of Cardiac Donation after Circulatory Death
06:26

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

8.3K
Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
04:55

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

1.3K

Area of Science:

  • Medical Ethics
  • Intensive Care Medicine
  • Organ Transplantation

Background:

  • Controlled donation after circulatory determination of death (cDCDD) is a key strategy to enhance organ availability.
  • France has utilized a national cDCDD protocol with abdominal normothermic regional perfusion (A-NRP) since 2015.
  • The potential for heart procurement from cDCDD donors has prompted renewed clinical and ethical discussions.

Purpose of the Study:

  • To provide a critical care perspective on the evolving practice of heart procurement from cDCDD donors.
  • To identify and address key challenges related to withdrawal of life-sustaining measures (WLSM) and normothermic regional perfusion (NRP).
  • To ensure ethical compliance and maintain public trust in the cDCDD pathway.

Main Methods:

  • This position paper is endorsed by two French intensive care societies.
  • It critically examines the implications of relocating WLSM for heart procurement.
  • It addresses concerns regarding the permanence of death and adherence to the dead donor rule during NRP.

Main Results:

  • Heart procurement may necessitate WLSM occurring outside the ICU, challenging current French practice.
  • Intensivists emphasize maintaining WLSM in the ICU and ensuring continuity of care during relocation.
  • Concerns about NRP and the dead donor rule can be mitigated through research and a strong ethical framework.

Conclusions:

  • Maintaining ICU-based WLSM is preferred, with a focus on patient care continuity if relocation is necessary.
  • Robust ethical guidelines and biomedical research are crucial to address concerns about death declaration and NRP.
  • Transparent discussion of these challenges is vital for sustaining trust in cDCDD.