Solid Pseudopapillary Neoplasm of the Diaphragm: A Case Report.

Area of Science:

• Oncology
• Pathology
• Surgical Case Reports

Background:

• Solid pseudopapillary neoplasms (SPNs) are rare pancreatic tumors, predominantly affecting young women.
• Extrapancreatic SPNs are exceptionally uncommon, with few documented cases in sites like the testis, paratesticular region, and ovary.
• To date, no SPN originating in the diaphragm has been reported in the English literature.

Purpose of the Study:

• To report the first documented case of a solid pseudopapillary neoplasm (SPN) originating in the diaphragm.
• To contribute to the understanding of extrapancreatic SPN behavior and presentation.

Main Methods:

• A case study of a 79-year-old female patient diagnosed with a liver lesion during routine follow-up.
• Diagnostic imaging utilizing 18F-fluorodeoxyglucose positron-emission tomography/computed tomography (18F-FDG PET/CT).
• Surgical resection of the diaphragmatic lesion followed by histopathological confirmation.

Main Results:

• A liver lesion initially detected via 18F-FDG PET/CT was surgically resected from the diaphragm.
• Pathological examination confirmed the lesion to be a solid pseudopapillary neoplasm (SPN).
• This represents the first reported instance of an SPN originating in the diaphragm.

Conclusions:

• Solid pseudopapillary neoplasms (SPNs) can occur in rare extrapancreatic locations, including the diaphragm.
• The case supports the theory that SPNs behave similarly regardless of their origin, whether pancreatic or extrapancreatic.
• This finding expands the known anatomical distribution of SPNs and highlights the importance of considering them in rare locations.