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Two new polyacetylenes from Bidens parviflora.

Chuan-Hou Li1,2,3, Guang-Hui Jiang4, Jing-Chun Yao1

  • 1State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Lunan Pharmaceutical Group Co., Ltd, Linyi 276005, China.

Journal of Asian Natural Products Research
|November 6, 2025
PubMed
Summary

Two new polyacetylenic compounds were isolated from Bidens parviflora, a plant used in traditional Dai medicine. Their structures were confirmed using advanced spectroscopic techniques.

Keywords:
AsteraceaeBidens parviflorapolyacetylenestructural confirmation specific rotation analysis

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Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Medicinal Plant Research

Background:

  • Bidens parviflora (Willd.) is utilized in traditional Dai medicine.
  • Polyacetylenic compounds are known for diverse biological activities.

Purpose of the Study:

  • To isolate and characterize novel polyacetylenic compounds from Bidens parviflora.
  • To contribute to the understanding of the chemical constituents of this ethnomedicinal plant.

Main Methods:

  • Extraction of aerial parts of Bidens parviflora using dichloromethane.
  • Separation and purification of compounds using chromatographic techniques.
  • Structural elucidation via UV, IR, HR-ESI-MS, 1D/2D NMR, and specific optical rotation measurements.

Main Results:

  • Two novel polyacetylenic compounds, (2R)-trideca-3E,5Z,11E-triene-7,9-diyne-1,2,13-triol (1) and (2R)-trideca-11E-ene-5,7,9-triyne-1,2,13-triol (2), were identified.
  • Comprehensive spectroscopic data confirmed the chemical structures of the isolated compounds.

Conclusions:

  • The study successfully identified two new polyacetylenic compounds from Bidens parviflora.
  • This research expands the knowledge of phytochemistry in ethnomedicinal plants.