Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

1.5K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.5K
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

213
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
213
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

215
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
215
Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

897
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
897
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

303
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
303
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

180
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
180

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of Hydrogen Plasma Treatment on the Electrical Behavior of Solution-Processed ZnO Thin Films.

Materials (Basel, Switzerland)·2024
Same author

Evidence-Based Application of Acupuncture for Pain Management in Companion Animal Medicine.

Veterinary sciences·2022
Same author

Towards Intelligently Designed Evolvable Processors.

Evolutionary computation·2022
Same author

Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules.

Scientific reports·2021
Same author

Comparison between methadone and buprenorphine within the QUAD protocol for perioperative analgesia in cats undergoing ovariohysterectomy.

Journal of feline medicine and surgery·2019
Same author

Low-Voltage Solution-Processed Hybrid Light-Emitting Transistors.

ACS applied materials & interfaces·2018

Related Experiment Video

Updated: Jan 12, 2026

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain
08:03

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

Published on: February 22, 2019

8.8K

Chronic Pain: Effective Relief Strategies for Geriatric Pets.

Michael C Petty1

  • 1Dogtor Consulting, LLC, Plymouth, MI, USA.

The Veterinary Clinics of North America. Small Animal Practice
|November 6, 2025
PubMed
Summary

Treating chronic pain in senior pets requires careful consideration of their health conditions to avoid adverse events. Thorough examinations are crucial for discussing effective therapeutic options and preventing premature euthanasia.

Keywords:
CanineCatChronic painDogFelineGeriatricPain

More Related Videos

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
08:33

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

1.6K
Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
08:23

Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats

Published on: March 13, 2012

60.4K

Related Experiment Videos

Last Updated: Jan 12, 2026

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain
08:03

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

Published on: February 22, 2019

8.8K
Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
08:33

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

1.6K
Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
08:23

Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats

Published on: March 13, 2012

60.4K

Area of Science:

  • Veterinary Medicine
  • Geriatric Animal Care
  • Pain Management

Background:

  • Chronic pain in geriatric dogs and cats presents unique challenges compared to younger animals.
  • Comorbidities in older pets significantly influence treatment choices and the risk of adverse events.
  • Untreated chronic pain can lead to decreased quality of life and difficult decisions regarding euthanasia.

Purpose of the Study:

  • To highlight the importance of specialized considerations for treating chronic pain in geriatric animals.
  • To emphasize the role of comorbidity assessment in managing pain and preventing adverse drug events.
  • To underscore the necessity of comprehensive orthopedic and neurologic evaluations for geriatric pets.

Main Methods:

  • Review of current literature on geriatric pain management in veterinary medicine.
  • Analysis of the impact of comorbidities on treatment protocols for chronic pain.
  • Emphasis on diagnostic approaches including orthopedic and neurologic examinations.

Main Results:

  • Geriatric animals require tailored pain management strategies due to age-related physiological changes.
  • Comorbidity screening is essential to identify potential contraindications and drug interactions.
  • Accurate diagnosis through detailed examinations guides the selection of appropriate and safe therapies.

Conclusions:

  • Specialized approaches are vital for effectively managing chronic pain in aging dogs and cats.
  • Integrating comorbidity assessment into pain management plans improves safety and efficacy.
  • Thorough diagnostic evaluations enable informed discussions about therapeutic options with pet owners.