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Assessment of changes in left ventricular myocardial work using the pressure strain loop after metabolic and
Shuai Li1, Yanping Zhang2, Yanxia Zhang1
1Department of Ultrasound, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, Shanxi Province, China.
Background:
Obesity is associated with impaired left ventricular myocardial function. Metabolic and bariatric surgery (MBS) is a potential intervention to improve cardiac function in individuals with obesity.
Objectives:
This study aimed to assess changes in left ventricular myocardial work in individuals with obesity following MBS using the pressure-strain loop method, providing a foundation for guiding clinical interventions.
Setting:
The study was conducted at a medical facility specializing in MBS and cardiovascular assessments.
Methods:
A total of 68 individuals with obesity (mean age 32.9 ± 6.0 years; 32 males) scheduled for MBS were prospectively enrolled, along with 48 healthy volunteers matched for age and sex (mean age 31.6 ± 5.6 years; 22 males) as the control group. Conventional echocardiographic parameters, global longitudinal strain (GLS), and myocardial work (MW) parameters were assessed for all participants both prior to MBS and 12 months postoperatively. MW parameters included global constructive work (GCW), global work index (GWI), global wasted work (GWW), and global work efficiency (GWE).
Results:
Twelve months postsurgery, reductions were observed in body mass index (BMI), blood pressure, blood glucose, blood lipids, and left ventricular mass index in the obesity group, although these remained higher than the control group. Improvements were noted in GLS, GCW, GWI, and GWE within the obesity group but remained lower than those of the control group. Conversely, GWW decreased but was still higher than that of the control group.
Conclusions:
MBS led to improvements in left ventricular systolic function due to weight reduction and metabolic enhancements; however, these improvements did not fully restore normal levels within 12 months postsurgery.
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