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In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
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Related Experiment Video

Updated: Jan 12, 2026

Minimally Invasive Embryo Transfer and Embryo Vitrification at the Optimal Embryo Stage in Rabbit Model
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Innovations in assisted reproductive technology through the advances in artificial intelligence and image processing.

Dayong Lee1,2

  • 1Department of Obstetrics and Gynecology, SMG-SNU Boramae Medical Center, Seoul, Korea.

Obstetrics & Gynecology Science
|November 7, 2025
PubMed
Summary
This summary is machine-generated.

Artificial intelligence (AI) and advanced imaging enhance assisted reproductive technology (ART) by improving embryo selection and ovarian monitoring. These innovations offer objective, reproducible assessments for better reproductive medicine outcomes.

Keywords:
Artificial intelligenceEmbryoIn vitro fertilizationReproductive medicineTime-lapse imaging

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Area of Science:

  • Reproductive Medicine
  • Biomedical Imaging
  • Artificial Intelligence

Background:

  • Traditional assisted reproductive technology (ART) methods for embryo selection and ovarian monitoring rely on subjective interpretation, leading to variability.
  • Artificial intelligence (AI) offers enhanced objectivity, consistency, and reproducibility in clinical decisions within reproductive medicine.

Purpose of the Study:

  • To explore the integration of AI and advanced imaging technologies in reproductive medicine.
  • To highlight the potential of AI and fluorescence lifetime imaging microscopy for objective embryo and follicle evaluation.
  • To discuss the application of AI in self-operated reproductive health monitoring.

Main Methods:

  • Utilizing AI-enhanced models for consistent performance in embryo selection and monitoring.
  • Employing fluorescence lifetime imaging microscopy for real-time, label-free metabolic assessment of gametes and embryos.
  • Developing AI-powered self-assessment tools for ovarian follicles using smartphone-compatible ultrasound devices.

Main Results:

  • AI models demonstrate reduced inter- and intra-observer variability compared to traditional methods.
  • Metabolic signatures from fluorescence lifetime imaging correlate with embryo developmental competence, offering non-invasive quality assessment.
  • AI facilitates automated follicle segmentation and self-assessment, improving ovarian stimulation tracking and patient engagement.

Conclusions:

  • The integration of AI, advanced image processing, and metabolic imaging represents a significant advancement in reproductive medicine.
  • These technologies enhance the precision of embryo and follicle evaluation.
  • Multimodal platforms combining clinical, morphological, and metabolic data hold promise for optimizing ART outcomes.