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A core outcome set for airway management research
Jan Hansel1,2, Alexander Fuchs3, Benjamin Cornwell4
1Division of Immunology, Immunity to Infection and Respiratory Medicine, The University of Manchester, Manchester, UK.
Anaesthesia
|November 7, 2025
Summary
This study developed a standardized core outcome set for airway management research. The new set includes 11 key outcomes and measurement instruments to improve data consistency and patient care.
Area of Science:
- Medical research methodology
- Anesthesiology
- Critical care medicine
Background:
- Airway management research historically lacks standardized outcome definitions, hindering evidence synthesis.
- Inconsistent outcomes impede progress in patient care and clinical practice.
Purpose of the Study:
- To develop a consensus-based core outcome set for airway management research.
- To standardize outcome selection and definitions for improved research and clinical application.
Main Methods:
- Systematic review of 4368 studies to identify candidate outcomes.
- Modified Delphi survey involving patients, clinicians, and other stakeholders across three rounds.
- Classification of outcomes into five domains: procedural effectiveness, physiological parameters, adverse events, patient-reported outcomes, and other.
Main Results:
- Identified 68 candidate outcomes from 100 studies.
- Engaged 453 participants in the first Delphi round and 155 in the second.
- Established an 11-item core outcome set including death, complications, success rates, and airway trauma, with agreed measurement instruments.
Conclusions:
- Presents the first consensus-based core outcome set for airway management research.
- Standardized definitions and measurement instruments will harmonize evidence synthesis.
- Improved translatability of findings to enhance clinical airway management practices.
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