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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Case Report: A rare case of thyroid metastasis from breast cancer
Xiaochuan Gao1, Mengxin Li1, Jinghui Hong1
1Department of Breast Surgery, General Surgery Center, First Hospital of Jilin University, Changchun, China.
Introduction:
To analyze the clinicopathological features, diagnosis, and treatment strategies for metastatic breast carcinoma to the thyroid (MBCT) to enhance clinical awareness of this rare condition.
Methods:
Analysis of clinical data from one MBCT patient and literature review.
Results:
A 41-year-old female with left breast invasive ductal carcinoma (IDC) received neoadjuvant AC-T chemotherapy, breast-conserving surgery, radiotherapy, and endocrine therapy. At eight years post-diagnosis, thyroid lesions were detected. Total thyroidectomy with lymph node dissection confirmed MBCT pathologically. No progression was observed at 16 months post-thyroidectomy.
Conclusions:
MBCT is a rare clinical entity characterized by nonspecific clinical and radiological findings. Immunohistochemical (IHC) analysis is essential for a definitive diagnosis. In patients with a breast cancer history, MBCT should always be considered in the differential diagnosis of thyroid abnormalities.
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