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Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue
Published on: July 28, 2023
The clinical application of ear keloid using five-blade core excision combined with pressure and superficial electron
Ying Qi1, Suling Xu1, Jieyi Wang2
1Department of Dermatology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
Background:
Surgical removal is the primary method for the clinical treatment of ear keloids. However, there are numerous surgical options available, and no standardized approach in the literature.
Objectives:
This study aimed to evaluate the impact of five-blade core excision on the removal of ear keloids.
Methods:
A preliminary study involving 11 patients (21 lesions) with ear keloids was conducted between January 2023 and December 2023. Five-blade core excision was performed; superficial electron beam radiotherapy was administered at a dose of 4 Gy for 5 post-operative consecutive days, and pressure clips were applied for 6 months. The Vancouver Scar Scale (VSS) and the Patient and Observer Scar Assessments Scale (POSAS) were used to assess the results.
Results:
The mean age of the patients was 24.36 years (18-44 years). Postoperative follow-up ranged from 20 months. The patients underwent 5 days of postoperative radiotherapy and pressure clips for 6 months. Nine patients had no recurrence, whereas two patients had a mild recurrence (one patient rejected radiotherapy). The VSS and POSAS scores significantly decreased (p < 0.01).
Conclusion:
Five-blade core excision combined with pressure and superficial electron beam radiotherapy demonstrates effective therapeutic outcomes for ear keloid.
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