Pertussis in the Tshwane District, Gauteng province, South Africa: A cross-sectional study
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View abstract on PubMed
Summary
This summary is machine-generated.Pertussis significantly impacts infants in Tshwane, South Africa, with most cases occurring before six months. Improved vaccination and surveillance are crucial to reduce pertussis (whooping cough) deaths.
Area Of Science
- Epidemiology
- Public Health
- Infectious Diseases
Background
- Pertussis (whooping cough) remains a global public health challenge, especially for infants and young children.
- Vaccination is effective, but access, coverage, and surveillance issues hinder control, particularly in low- and middle-income countries.
Purpose Of The Study
- To analyze the demographic, geographic, and seasonal patterns of pertussis cases in Tshwane District, Gauteng, South Africa.
- To identify trends and vulnerable populations affected by pertussis from 2015 to 2019.
Main Methods
- Retrospective cross-sectional analysis of pertussis surveillance data from January 2015 to December 2019.
- Data sourced from the Tshwane Pertussis Monitoring Database and validated against the District Health Information System.
- Descriptive statistics, chi-square tests, and time-series analyses were employed.
Main Results
- A total of 272 pertussis cases were reported, with 46.7% affecting infants under one year old.
- Infants younger than six months accounted for 39.7% of cases; one-third of all cases required hospitalization, primarily infants.
- Most notifications came from private facilities (73.5%), with peaks observed in spring-summer. Three infant deaths were recorded.
Conclusions
- Pertussis significantly contributes to the disease burden in Tshwane, with a high impact on early infancy.
- Strengthening immunization programs, enhancing surveillance systems, and ensuring equitable diagnostic access are vital for reducing pertussis morbidity and mortality.
- The study highlights inequities in vaccination reporting and diagnostic access, informing strategies to improve pertussis control.
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