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Updated: Jan 12, 2026

Developing Photosensitizer-Cobaloxime Hybrids for Solar-Driven H2 Production in Aqueous Aerobic Conditions
Published on: October 5, 2019
Electron-Mediator-Free Microfluidic Photocatalytic Coenzyme Regeneration with 100% Conversion Efficiency within 126 S
Yao Chai1, Liang Wan1, Zirui Pang1
1Department of Applied Physics, The Hong Kong Polytechnic University, Hong Kong, Kowloon, 999077, China.
None:
Microfluidic systems enhance photocatalytic efficiency through superior mass/energy transfer and precise parameter control. Here, an electron-mediator-free microfluidic platform is designed for photocatalytic coenzyme NAD(P)H regeneration by integrating ultrathin BiOBr nanosheets. This architecture enables direct electron-proton coupling, achieving 100% NAD+ conversion within 126 s with exceptional selectivity (72.30%) for bioactive 1,4-NADH. Continuous operation over 32 h shows no activity decay, demonstrating unparalleled stability. This study establishes a benchmark for designing integrated photocatalytic systems and highlights their broad potential for applications in biocatalysis, synthetic biology, and renewable energy.
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