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Updated: Jan 12, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
Hybrid Pulmonary Valve Replacement in Very Large Right Ventricular Outflow Tract Using a Self-Expanding Valve
Damien Schaffner1, Mi-Young Cho2, Maren Kleine-Brueggeney3
1Deutsches Herzzentrum der Charité, Department of Congenital Heart Disease-Pediatric Cardiology, Berlin, Germany; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Background:
Patients with very large right ventricular outflow tract (RVOT) may not be suitable for percutaneous pulmonary valve implantation (PPVI). Hybrid PPVI, combining surgical pulmonary artery plication with transcatheter valve implantation, may offer a feasible alternative to surgical valve replacement for high-risk patients.
Case Summary:
We report the first hybrid PPVI using the Venus P-Valve (Venus Medtech) in a 60-year-old man with very large RVOT and severe biventricular dysfunction, as well as his follow-up at 5 months.
Discussion:
This case demonstrates the feasibility of hybrid PPVI with pulmonary artery plication and a self-expanding valve in patients with very large RVOT.
Take-Home Message:
Hybrid PPVI using a self-expanding valve is a feasible approach allowing pulmonary revalvulation in patients with high operative risk and pulmonary artery dimensions unsuitably large for commercially available transcatheter pulmonary valves.

