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Patterns of Recurrence and Oncologic Outcomes After Maxillectomy: Does Reconstructive Modality Matter?

Cameron Lee1, Salim Abdul Wasay2, Glyndwr Jenkins3

  • 1Assistant Professor, Department of Oral and Maxillofacial Surgery, University of Maryland Medical Center, Baltimore, MD.

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
|November 7, 2025
PubMed
Summary
This summary is machine-generated.

Reconstruction method after maxillectomy for oral cancer does not impact recurrence detection or survival. Both obturator and native tissue reconstructions showed similar outcomes for oral cavity malignancies.

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Area of Science:

  • Oral oncology
  • Maxillofacial surgery
  • Reconstructive surgery

Background:

  • Reconstruction after maxillectomy is crucial for oral cancer patients.
  • Concerns exist that reconstructive methods may affect recurrence detection and outcomes.

Purpose of the Study:

  • To evaluate the association between reconstructive modality and time to local recurrence detection.
  • To assess the impact of reconstruction on survival outcomes in maxillectomy patients.

Main Methods:

  • Retrospective cohort study of 154 patients undergoing maxillectomy for oral malignancy.
  • Compared obturator reconstruction versus native tissue reconstruction (local, regional, free flap).
  • Analyzed local disease-free survival, overall survival, and recurrence detection methods.

Main Results:

  • No significant difference in local disease-free survival or overall survival based on reconstructive modality.
  • Recurrence detection (clinical vs. radiographic) and resectability were also not significantly associated with reconstruction type.
  • Local recurrence occurred in 26.6% of patients, with similar rates between obturator and native tissue groups.

Conclusions:

  • Reconstructive modality following maxillectomy does not influence the timeliness of local recurrence detection.
  • Choice of reconstruction (obturator vs. native tissue) does not negatively impact survival outcomes for oral cavity malignancies.