Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From Clinical Heterogeneity to National Standardization in Liver Transplantation for Perihilar Cholangiocarcinoma: The LITALHICA Protocol.

Transplantation·2026
Same author

A new regulatory framework: impact of the SoHO Regulation for medically assisted reproduction.

Human reproduction (Oxford, England)·2026
Same author

Is Warm Ischemic Time no Longer an Absolute Cutoff in Organ Donation After Circulatory Determination of Death? The Italian Experience of Prolonged "No-touch" Period.

Transplantation·2026
Same author

Risk factors for disease generalization in acetylcholine receptor antibody-positive ocular myasthenia: a multicenter retrospective study.

Frontiers in neurology·2026
Same author

Clinical significance of incidental pericardial late gadolinium enhancement on cardiac magnetic resonance.

International journal of cardiology·2026
Same author

4th workshop purification therapies, from research to clinics "the end of the beginning": executive summary.

Transplant international : official journal of the European Society for Organ Transplantation·2026

Related Experiment Video

Updated: Jun 9, 2026

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
11:49

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Published on: May 2, 2013

Donors Infectious Risk Stratification: Activity of the Italian National Transplant Center.

Elena Graziano1, Maddalena Peghin1, Maria Luisa Balsamo1

  • 1Infectious and Tropical Diseases Unit, Department of Medicine and Surgery, University of Insubria, ASST Sette Laghi, Varese, Italy.

Transplant Infectious Disease : an Official Journal of the Transplantation Society
|November 7, 2025
PubMed
Summary
This summary is machine-generated.

Infectious disease second opinion (IDSO) evaluations accepted nearly 95% of organ donors, expanding the donor pool. Further studies are needed to assess the impact of donors with increased infectious risk on transplant recipients.

Keywords:
consultationdonationdonor‐derived infectionstransplant infectious disease

More Related Videos

In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients
18:48

In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients

Published on: August 12, 2017

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

Related Experiment Videos

Last Updated: Jun 9, 2026

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
11:49

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Published on: May 2, 2013

In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients
18:48

In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients

Published on: August 12, 2017

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

Area of Science:

  • Transplant Surgery
  • Infectious Diseases
  • Public Health

Background:

  • Expanding the organ donor pool is crucial for transplantation.
  • Donors with increased infectious risk require careful evaluation.
  • The Italian National Transplant Center (CNT) utilizes an expert task force for complex infectious assessments.

Purpose of the Study:

  • To describe the activity of the infectious disease second opinion (IDSO) task force.
  • To analyze the infectious risk assessment of potential organ donors.
  • To evaluate the impact of IDSO on donor pool acceptance.

Main Methods:

  • Retrospective observational study of IDSO activity from June 2022 to October 2023.
  • Analysis of donor infectious risk levels categorized according to the CNT protocol.
  • Review of infectious problems, risk classifications, and organ exclusion reasons.

Main Results:

  • IDSO was requested for 30% of donors (1246/4153).
  • Most donors had acceptable increased infectious risk (60.8%); only 5.2% were deemed unacceptable.
  • Pneumonia, inflammatory marker elevation, and bacteremia were common infectious issues. Lung was the most excluded organ (18.2%).

Conclusions:

  • IDSO activity facilitated the acceptance of nearly 95% of evaluated donors.
  • Additional testing and therapeutic indications were provided for a significant number of donors and recipients.
  • Prospective international research is essential to determine the outcomes for recipients receiving organs from donors with increased infectious risk.