Related Experiment Video
Updated: Jan 12, 2026
Confocal Imaging of Neuropeptide Y-pHluorin: A Technique to Visualize Insulin Granule Exocytosis in Intact Murine and Human Islets
Published on: September 13, 2017
Soft X-ray tomography illuminates drug-induced changes in insulin granules
Natalia Fuchs1, Venera Weinhardt2
1Centre for Organismal Studies, Heidelberg University, Heidelberg, Germany.
None:
In this issue of Structure, Deshmukh et al.1 reveal that β cells actively remodel insulin secretory granules in response to specific physiological cues, altering granule density, proinsulin processing, and spatial distribution. This stimulus-specific structural maturation highlights how β cells sculpt their secretory machinery, offering new insights into insulin release regulation.
More Related Videos
15:18Near Infrared Optical Projection Tomography for Assessments of β-cell Mass Distribution in Diabetes Research
Published on: January 12, 2013
09:07Longitudinal In Vivo Imaging and Quantification of Human Pancreatic Islet Grafting and Contributing Host Cells in the Anterior Eye Chamber
Published on: June 11, 2020
