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The Relationship Between Insulin Resistance and Cancer in Humans.

María M Adeva-Andany1, Lucia Adeva-Contreras2, Eva Ameneiros-Rodriguez1

  • 1Internal Medicine, Hospital Juan Cardona, Ferrol, Spain.

Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme
|November 7, 2025
PubMed
Summary

Insulin resistance is linked to cancer development, as cancer cells switch to glycolysis for rapid growth. This metabolic change, driven by factors like hypoxia-inducible factor-1 and cytokines, impairs the body's response to insulin.

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