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Task optimized vision transformer for diabetic retinopathy detection and classification in resource constrained early
Ramasubramanian Bhoopalan1, Priyadharshini Sekar1, N Nagaprasad2
1Department of Electronics and Communication Engineering, SRM TRP Engineering College, Irungalur, Tamil Nadu, India.
Scientific Reports
|November 7, 2025
Summary
A new Task-Optimized Vision Transformer (TOViT) model effectively detects Diabetic Retinopathy (DR) and classifies its severity. This efficient AI enables real-time screening on low-cost hardware, improving access to early diagnosis.
Area of Science:
- Ophthalmology
- Artificial Intelligence
- Medical Imaging
Background:
- Diabetic Retinopathy (DR) is a major cause of preventable blindness globally.
- Early DR detection and classification are crucial but challenging, especially in resource-limited areas.
- Existing deep learning models struggle with long-range dependencies and computational demands for DR analysis.
Purpose of the Study:
- To develop an efficient AI model for Diabetic Retinopathy detection and severity classification.
- To optimize a Vision Transformer model for enhanced feature extraction and computational efficiency.
- To enable real-time DR screening on low-cost hardware like Raspberry Pi-4.
Main Methods:
- Introduced a Task-Optimized Vision Transformer (TOViT) model with optimized learning rates, attention heads, and embedding dimensions.
- Employed structured pruning and 8-bit quantization for model compression.
- Evaluated performance on three large-scale public datasets and implemented on Raspberry Pi-4 hardware.
Main Results:
- Achieved 99% classification accuracy and F1-scores over 93% across all DR stages.
- Demonstrated real-time performance on Raspberry Pi-4, processing at 8 frames per second with 120 ms latency.
- Confirmed the model's suitability for portable, point-of-care screening devices.
Conclusions:
- The TOViT model offers a scalable and clinically relevant solution for automated DR diagnosis.
- Optimized AI models can overcome computational limitations of traditional deep learning for medical imaging.
- This approach has significant potential to expand access to early retinal screening in global healthcare systems.

