Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

7.5K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
7.5K
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

940
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by...
940
Respiratory Assessment: Purpose and Indications01:19

Respiratory Assessment: Purpose and Indications

1.7K
Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.7K
Vitamins01:30

Vitamins

2.3K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
2.3K
Common Respiratory Disorders01:31

Common Respiratory Disorders

1.3K
Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
1.3K
Breathing01:05

Breathing

64.1K
The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
64.1K
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Paediatrics
  9. Infant And Child Health
  11. Association Between Prenatal Vitamin D Supplementation And Respiratory Diseases In Children: A Systematic Review And Meta-analysis

Association between prenatal vitamin D supplementation and respiratory diseases in children: a systematic review and meta-analysis

Jieru Shen1, Zhonghui Zhou1, Fao Feng2

  • 1Department of Respiratory, Ningbo Municipal Hospital of Traditional Chinese Medicine (TCM), Affiliated Hospital of Zhejiang Chinese Medical University, No.819, Liyuan North Road, Haishu District, Ningbo, 315010, China.

BMC Pediatrics
|November 7, 2025

Related Experiment Videos

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

10.8K
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

11.0K
Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
03:19

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

713

View abstract on PubMed

Summary
This summary is machine-generated.

Maternal vitamin D supplementation during pregnancy does not significantly impact respiratory or allergy-related outcomes in children. This meta-analysis found no evidence of benefit for conditions like asthma, wheezing, or eczema.

Area of Science:

  • Immunology
  • Pediatrics
  • Public Health

Background:

  • Maternal vitamin D status during pregnancy is crucial for offspring well-being, potentially influencing immunomodulation and respiratory health.
  • Existing evidence on vitamin D's effects on respiratory and allergy-related outcomes in children is conflicting.
  • A comprehensive synthesis of data is needed to clarify the role of prenatal vitamin D supplementation.

Purpose of the Study:

  • To systematically review and synthesize evidence from randomized controlled trials (RCTs) on the effects of maternal vitamin D intake during pregnancy.
  • To evaluate the impact of prenatal vitamin D supplementation on respiratory and allergy-related outcomes in children.
  • To provide a clear direction based on synthesized evidence regarding vitamin D's role in child respiratory and allergic health.

Main Methods:

Keywords:
Meta-analysisRespiratory outcomeSystematic reviewVitamin d

Related Experiment Videos

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

10.8K
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

11.0K
Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
03:19

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

713
  • Conducted systematic searches across major databases (PubMed, Scopus, Web of Science, Cochrane Library) until August 2025.
  • Included randomized controlled trials (RCTs) assessing maternal vitamin D intake during pregnancy and child outcomes.
  • Evaluated evidence quality using the GRADE method and study quality using the Cochrane risk-of-bias tool.

Main Results:

  • Seven RCTs were included in the analysis.
  • Prenatal vitamin D supplementation showed no significant effect on respiratory outcomes, including respiratory tract infections (RTI), asthma, and wheezing.
  • No significant association was found between maternal vitamin D supplementation and eczema, allergic conditions, or immunoglobulin E (IgE) levels in children.

Conclusions:

  • Maternal vitamin D supplementation during pregnancy does not demonstrate a significant impact on respiratory or allergy-related outcomes in children.
  • The current evidence suggests no benefit of prenatal vitamin D supplementation for preventing common respiratory and allergic conditions in offspring.
  • Further research may be warranted to explore specific subgroups or alternative vitamin D supplementation strategies.