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Updated: May 4, 2026
Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs
Published on: May 24, 2016
Tracheal metastasis from primary oral malignant melanoma: A case report
Yun Liu1, Wenwen Guo2, Shanshan Zhang1
1Clinical Medical College, Jining Medical University, Jining, Shandong, PR China.
Rationale:
Oral malignant melanoma (OMM) is a rare but highly aggressive malignancy that frequently metastasizes to the lymph nodes, lungs, liver, brain, and bones; however, tracheal metastasis is uncommon. Such cases are rarely reported.
Patient Concerns:
A 58-year-old man with a history of primary oral melanoma treated with surgery followed by radiotherapy and chemotherapy 2 years prior presented with respiratory symptoms. Chest computed tomography and bronchoscopy revealed a pigmented neoplasm obstructing the main trachea of the patient. Histopathological and immunohistochemical analyses of the neoplasm confirmed the presence of metastatic melanoma.
Diagnoses:
Tracheal metastasis of OMM.
Interventions:
Complete resection of the lesion within the tracheal lumen was achieved using high-frequency electrocautery snare resection via bronchoscopy.
Outcomes:
The patient's airway was reestablished, and the symptoms of respiratory distress were alleviated.
Lessons:
Clinicians should be alert to the possibility of tracheal metastasis in patients with OMM presenting with nonspecific respiratory manifestations.
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