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Related Experiment Video

Updated: Jan 6, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
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Craniopharyngioma - What's next.

Hermann L Müller1

  • 1Department of Pediatrics and Pediatric Hematology/Oncology, University Children's Hospital, Carl von Ossietzky Universität Oldenburg, Klinikum Oldenburg AöR, Rahel-Straus-Strasse 10, Oldenburg, 26133, Germany. hermann.mueller@ymail.com.

Pituitary
|November 8, 2025
PubMed
Summary

Craniopharyngioma treatment can cause hypothalamic obesity, a complex syndrome impacting multiple body systems. New personalized algorithms and medications show promise for managing this challenging condition.

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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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Same author

Current Approaches and Therapeutic Strategies for Hypothalamic Syndrome in Patients with Childhood-onset Craniopharyngioma.

Journal of clinical research in pediatric endocrinology·2026
Same author

Diagnostic criteria for acquired hypothalamic obesity - international expert guidance document.

Endocrine journal·2025
Same author

Sleep Disorders, Dysregulation of Circadian Rhythms, and Fatigue After Craniopharyngioma-A Narrative Review.

Biomedicines·2025
Same author

Semaglutide treatment in hypothalamic obesity: Two-Year outcomes on body composition, appetite, and quality of life.

Pituitary·2025
Same author

Prolactin serum concentrations in childhood-onset craniopharyngioma patients.

Journal of endocrinological investigation·2025
Same author

Economics of hypothalamic obesity in patients with craniopharyngioma and other rare sellar/suprasellar tumors.

The European journal of health economics : HEPAC : health economics in prevention and care·2025

Area of Science:

  • Neuroendocrinology
  • Oncology
  • Metabolic Medicine

Background:

  • Craniopharyngioma diagnosis often leads to rapid weight gain and hypothalamic obesity.
  • Hypothalamic obesity is part of a broader hypothalamic syndrome with diverse neuroendocrine and physiological impairments.
  • This condition significantly increases risks for metabolic syndrome, cardiovascular disease, and reduced quality of life.
Keywords:
HypothalamusIrradiationMetabolic syndromeNeurosurgeryObesityQuality of life

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