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A Modified Murine Heterotopic Heart Transplant Protocol Matching Contemporary Standards of Aseptic Technique, Anesthesia, and Analgesia
Published on: September 28, 2022
Improving timely transplantation while reducing cancellation of scheduled surgery
John K Peel1, Jennifer Whiteley2, Terri Stuart-McEwan3
1Department of Anesthesiology, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Background:
Organ transplant programs must mobilize perioperative resources at short notice, a stress to the system that is frequently managed by cancelling scheduled operations. We performed a quality-improvement initiative to restructure surgical services at one of the largest multi-organ transplant programs in North America (Toronto General Hospital, University Health Network, Toronto, Canada) by adapting the system developed by the Institute for Healthcare Optimization.
Methods:
The resultant University Health Network Institute for Healthcare Optimization system involved (1) dedication of 2 emergency (standby) operating rooms for urgent/emergency cases and (2) revised and formalized standards to classify transplant urgency. We performed a retrospective, before-after, single-center study to measure the impact of our initiative on access to transplantation and use of operating room resources.
Results:
After the University Health Network Institute for Healthcare Optimization system was implemented, we observed a significant reduction in cancellation of scheduled surgeries per month (3% [2.4%-3.6%] vs 9% [8.1%-9.4%]; P < .001), with transplant recipients more likely to enter the operating room within the target time (P < .001 for all organ types), no increased likelihood of after-hours transplantation, and no decrease in the number of scheduled cases completed each month (715 ± 156 operations vs 729 ± 50 operations; P = .684).
Conclusions:
The University Health Network Institute for Healthcare Optimization system has allowed our center to accommodate increasing transplant volumes without negatively impacting other surgical services.
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