Translating Adult Electrophysiology Technology to Pediatric and Congenital Electrophysiology

Edward O'Leary ¹, Natasja M S de Groot ²

⁰Division of Electrophysiology, Department of Cardiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.

Cardiac Electrophysiology Clinics +

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November 8, 2025

View abstract on PubMed

Summary

Translating adult electrophysiology therapies to pediatric congenital heart disease (CHD) populations presents unique challenges. This review explores these hurdles and evaluates innovative technologies for pediatric application.

Area Of Science

Cardiology
Pediatric Electrophysiology
Congenital Heart Disease

Background

Adult electrophysiology therapies are advancing rapidly.
Pediatric and congenital heart disease (CHD) populations have unique physiological characteristics.
Translating adult innovations to pediatrics requires careful consideration.

Purpose Of The Study

To review the current status of translating adult electrophysiologic therapies to pediatric and CHD patients.
To identify and analyze the specific challenges in pediatric electrophysiology.
To assess the potential utility of advanced electrophysiologic technologies in young patients.

Main Methods

Literature review of current electrophysiologic therapies and technologies.
Analysis of challenges specific to pediatric and CHD electrophysiology.
Evaluation of adult innovations for pediatric applicability.

Main Results

Pediatric electrophysiology faces challenges related to patient size, anatomy, and arrhythmia substrate.
Existing adult technologies may require adaptation for pediatric use.
Innovative approaches are needed to bridge the gap between adult and pediatric electrophysiology.

Conclusions

Successful translation of electrophysiologic therapies requires addressing pediatric-specific challenges.
Further research and technological adaptation are crucial for advancing pediatric electrophysiology.
Optimizing treatments for pediatric and CHD patients is essential for improving outcomes.

Keywords:

Cardiac devices Pulse field ablation Remote magnetic navigation