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Corrigendum to "HER2 expression in a molecularly defined cohort of endometrial cancer patients: The SPECTRUM study"

Alfonso Cortés-Salgado1, Esther Moreno-Moreno2, Irene Carretero-Barrio3

  • 1Department of Medical Oncology, Ramón y Cajal University Hospital, Ramón y Cajal Health Research Institute (IRYCIS), Madrid, Spain; Faculty of Medicine, Alcalá University, Alcalá de Henares, Spain.

Gynecologic Oncology
|November 9, 2025
PubMed
Abstract

No abstract available in PubMed .

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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