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Predicting Efficacy of Virtual Reality-Based Stabilization for Individuals With Posttraumatic Stress Symptoms: A
Yongmin Shin1, Euijin Kim2, Kibum Kim2
1Department of Psychology, Gachon University, Seongnam, Republic of Korea.
Psychiatry Investigation
|November 9, 2025
Summary
Virtual reality-based stabilization (VRS) effectively reduced posttraumatic stress symptoms (PTSS) and improved mental health in COVID-19 survivors and healthcare workers. Machine learning models accurately predicted intervention effectiveness, enabling personalized mental health support.
Area of Science:
- Mental Health
- Psychological Interventions
- Virtual Reality Applications
Background:
- Respiratory infectious diseases, like COVID-19, caused significant mental health challenges globally.
- There is a critical need for proactive psychological interventions to prepare for future pandemics.
- Virtual reality-based stabilization (VRS) was developed to mitigate posttraumatic stress symptoms (PTSS) and related comorbidities.
Purpose of the Study:
- To evaluate the effectiveness of VRS in COVID-19 survivors and healthcare workers.
- To predict the impact of VRS on PTSS and depression using machine learning.
- To identify factors influencing VRS effectiveness for personalized interventions.
Main Methods:
- A study involving 43 COVID-19 survivors and healthcare workers assessed VRS effectiveness over five sessions.
- Pre- and post-intervention psychological assessments measured PTSS, depression, anxiety, COVID-related fear, posttraumatic growth, and quality of life.
- A machine learning model predicted changes in PTSS and depression using baseline assessments and heart rate variability.
Main Results:
- VRS significantly improved all measured psychological outcomes post-intervention.
- The machine learning model showed good predictive accuracy (R2=0.414-0.723) for PTSS and depression changes.
- Higher baseline PTSS, elevated heart rate variability, and younger age correlated with greater improvement.
Conclusions:
- VRS is an effective intervention for PTSS and associated mental health conditions.
- Integrating clinical and demographic data enhances prediction models for personalized mental healthcare.
- VRS offers a promising approach for psychological support during and after pandemics.

