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Post-Translational modifications and proteomic mechanisms underlying substance use disorder

Songjukta Chakraborty1, Anastasia Dodge1, Mason Hochstetler1

  • 1Department of Pharmacology and Physiology, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.

Neuroscience
|November 9, 2025
PubMed
Summary

Post-translational modifications (PTMs) are key drivers of neurobiological changes in Substance Use Disorder (SUD). Targeting PTMs offers a promising therapeutic strategy for SUD treatment.

Keywords:
NeuroplasticityRelapseSubstance use disorder (SUD)Targeted therapiespost-translational modifications (PTMs)

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