Access-Site Closure with a Kaolin-Filled Pad after Intervention with Large Access Sheaths-A Retrospective...

This report summarizes our initial experience with QuikClot Interventional Hemostatic Bandage (QCI) under thrombocyte aggregation inhibition following interventional procedures using 8-French catheters or larger, and investigates the feasibility, efficacy, and safety of procedures conducted on 27 patients.

We performed a retrospective analysis of patients who underwent QCI application after interventional procedures using 8F catheters or larger between February 16, 2021 and January 20, 2025, at a tertiary referral center.

Of the 27 patients included, 20 were males. The mean age was 69 ± 10.2 years, and the mean body mass index was 24.6 kg/m² (±4.1 kg/m²). Of the 27, 15 procedures performed were peripheral interventions for peripheral arterial disease. The most common access sheath size was 8F (23/27), and the maximum size was 14F. The technical success rate of the QCI application was 100%. In all patients, a false aneurysm in need of revision could be excluded via sonography. QCI-associated complication rate was 3.7%. One surgical revision was performed within the first 30 days. One case of mortality (1/27) was unlikely to be associated with the vascular closure device.

The present study demonstrated that using QCI for access-site closure is easy and effective in combination with manual compression and a pressure bandage, even in cases of large-bore arteriotomies (≥8F) and under thrombocyte aggregation inhibition.