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Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Anterior Closing Wedge Osteotomies for Anterior Cruciate Ligament Deficiency: Indications, Technique, and Outcomes
Amedeo Guarino1, Nicolas Cance2, Edoardo Giovannetti de Sanctis3
1Department of public Health, Universita' degli Studi di Napoli Federico II, Via S.Pansini 5, Naples, NA, Italy, 80131.
Abstract:
Anterior cruciate ligament (ACL) deficiency leads to knee instability and increased joint degeneration. While ACL reconstruction (ACLR) is common, a steep posterior tibial slope (PTS) raises the risk of graft failure. Anterior closing wedge osteotomy (ACWO), or tibial deflexion osteotomy, is an effective surgical option for high PTS, especially in revision cases. ACWO alters tibial slope, reducing strain on ACL grafts and improving stability. With excellent long-term outcomes, including low rerupture rates and good return-to-sport results, ACWO is effective in cases with increased tibial slope and static anterior tibial translation, though its role in primary ACLR is still debated.
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