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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

816
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
530
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

469
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
469
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

908
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
908
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

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Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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Tuberculosis: An Ongoing Global Threat.

Parissa Farnia1, Ali Akbar Velayati2, Jalaledin Ghanavi2

  • 1Shahid Beheshti University of Medical Sciences, Mycobacteriology Research Centre (MRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Tehran, Iran. farnia@theaasm.org.

Advances in Experimental Medicine and Biology
|November 9, 2025
PubMed
Summary
This summary is machine-generated.

Tuberculosis (TB) is a major global health threat, with millions affected annually. Addressing socioeconomic factors, drug resistance, and pandemic disruptions is crucial for TB elimination.

Keywords:
AgeGenderIncidenceMycobacterium tuberculosisPopulation dynamicsTB control program

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Area of Science:

  • Public Health
  • Infectious Diseases
  • Global Health

Background:

  • Tuberculosis (TB) presents a significant global health burden, impacting millions yearly and causing substantial mortality.
  • High TB incidence rates are concentrated in low- and middle-income countries, exacerbated by socioeconomic factors like poverty and poor living conditions.
  • Drug-resistant TB strains (MDR-TB, XDR-TB, TDR-TB) and COVID-19 disruptions complicate treatment and control efforts, reversing progress.

Purpose of the Study:

  • To highlight the persistent global challenge of tuberculosis (TB).
  • To underscore the impact of socioeconomic determinants and drug resistance on TB control.
  • To emphasize the need for comprehensive strategies to achieve TB elimination.

Main Methods:

  • Analysis of data from the WHO Global Tuberculosis Report 2024.
  • Review of factors contributing to TB transmission and treatment challenges.
  • Assessment of the impact of the COVID-19 pandemic on TB services.

Main Results:

  • In 2023, 10.6 million people developed TB, leading to 1.6 million deaths.
  • Socioeconomic factors and drug-resistant TB strains significantly worsen outcomes and increase costs.
  • The COVID-19 pandemic has negatively impacted TB case detection and treatment continuity.

Conclusions:

  • Coordinated, multisectoral strategies are essential for TB elimination.
  • Addressing socioeconomic barriers, improving diagnostics, and combating stigma are critical.
  • Investment in research for new prevention and treatment tools is vital to meet WHO End TB Strategy targets.