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Differentiation of cisplatin uptake within a population of cancer cells - how to "crack this nut" using single-cell
Zuzanna Szymańska1, Magdalena Matczuk1, Agnieszka Żuchowska2
1Chair of Analytical Chemistry, Warsaw University of Technology, Noakowskiego St. 3, 00-664 Warsaw, Poland. magdalena.matczuk@pw.edu.pl.
The Analyst
|November 10, 2025
Abstract:
A versatile tool to unravel the uptake diversity of a front-line anticancer drug, cisplatin, within a cancer cell population is proposed herein based on single-cell inductively coupled plasma mass spectrometry. The interested researcher is provided with a tutorial to help adapt such cutting-edge methodology and know-how to reliable data processing.

