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Right ventricular pressure-volume loop analysis in congenital heart disease
Renée S Joosen1, Michael G Dickinson2, Marielle C van de Veerdonk3
1Department of Pediatric Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
International Journal of Cardiology. Congenital Heart Disease
|November 10, 2025
Summary
Right ventricular (RV) pressure-volume loop analysis using the multi-beat method is a safe and reliable tool for assessing RV function in complex congenital heart disease (CHD) patients. This method provides crucial insights into RV adaptation, aiding in improved patient management.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Cardiac Physiology
Background:
- Right ventricular (RV) function is a key prognostic indicator in congenital heart disease (CHD).
- Current methods for assessing RV function are limited by load dependency.
- RV pressure-volume (PV) loop analysis is a load-independent gold standard but can be time-consuming and variable.
Purpose of the Study:
- To provide a comprehensive guide on performing RV PV loop analysis using the multi-beat method.
- To detail the application of this technique in pediatric and adult patients with complex CHD.
Main Methods:
- Utilizing the multi-beat method for RV pressure-volume loop analysis.
- Application in pediatric and adult patient populations with complex CHD.
Main Results:
- RV PV loop analysis via the multi-beat method is safe and reliable in children and adults with complex CHD.
- The technique allows for accurate assessment of RV adaptation to pressure and/or volume overload.
Conclusions:
- RV PV loop analysis is a valuable tool for understanding RV adaptation and cardiac physiology in complex CHD.
- This approach can enhance patient management and optimize treatment strategies for improved outcomes.
